2-Thiopheneacetic acid, α-amino-5-methyl- - Names and Identifiers
2-Thiopheneacetic acid, α-amino-5-methyl- - Physico-chemical Properties
Molecular Formula | C7H9NO2S
|
Molar Mass | 171.22 |
Density | 1.347 |
Storage Condition | 2-8°C |
2-Thiopheneacetic acid, α-amino-5-methyl- - Introduction
2-(5-Methylthiophen-2-yl)glycine is an organic compound whose chemical formula is C9H9NO2S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-(5-Methylthiophen-2-yl)glycine is a white to pale yellow crystalline solid.
-Solubility: Slightly soluble in water, soluble in organic solvents such as alcohols and chlorinated solvents.
-Melting point: Its melting point range is 172-173°C.
-Stability: The compound is stable at room temperature, but should avoid contact with oxidizing agents.
Use:
One of the main uses of 2-(5-Methylthiophen-2-yl)glycine is as an intermediate in organic synthesis. It can be used in the synthesis of compounds containing a 2-methylthiophene group. In addition, the compound can also be used as a raw material for dyes, fluorescent probes, pharmaceutical chemicals, etc.
Preparation Method:
2-(5-Methylthiophen-2-yl)glycine can be synthesized by the following steps:
1. Add 5-methyl -2-thiophene acetic acid to anhydrous acetonitrile and heat to dissolve.
2. Add ammonia to the solution, and then stir to react for 2-3 hours.
3. The reaction mixture was filtered and cooled to give the crystalline product.
4. The product was washed with cold acetonitrile and dried to obtain pure product.
Safety Information:
- 2-(5-Methylthiophen-2-yl)glycine is less toxic, but care should be taken to prevent inhalation, ingestion, and contact with skin and eyes.
-Wear appropriate protective equipment, such as lab gloves and goggles, when handling the compound.
-During storage and use, avoid contact with oxidants and strong acids to prevent dangerous reactions.
-When operating in a laboratory environment, relevant safe operating procedures and standards should be followed.
Last Update:2024-04-09 02:00:49